Nix led the Bern Nix trio from 1985 to his death in 2017. In 1993, the band released the album Alarms and Excursions. The album made many critics’ top ten lists. Nix released a solo recording entitled Low Barometer (Tompkins Square Records) which became available online in September 2006. Another recent Nix composition, “Les is More”, appears on Art and Money, an album released by 1687, Inc. in 2006. In 2013, the Bern Nix Quartet released an album entitled Negative Capability.
Nix also performed with James Chance and the Contortions and appears on their 1981 Live in New York recording. He has also appeared with Jayne Cortez, John Zorn, Marc Ribot, Elliott Sharp, Jemeel Moondoc, Ronald Shannon Jackson, James Chance, and Kip Hanrahan.